Gas Chromatography Mass Spectrometer

Gas chromatography mass spectrometer (GCMS) is an analytical technique that combines the separation properties of gas chromatography with the detection feature of mass spectrometry to identify different substances within a test sample.

Gas chromatography is used to separate the volatile and thermally stable organic compounds in a sample whereas MS fragments the analyte and identifies it by matching the mass of breakdown products through a mass spectrometry compound database.

Quantification of known compounds is then performed using a calibration curve using various concentrations of standards.