We create and distribute software and IT tools for the computational biology research community
The KIR*IMP method will allow you to impute various KIR types using your data, including KIR gene copy number, KIR A or B haplotype and gene-content haplotypes.
Fast computation of LD-Adjusted SNP weights and Kinship matrices for genome-wide mixed-model analysis. Includes a generalised REML Solver and efficient gene-based association testing.
likeLTD is an R package for computing likelihoods for DNA profile evidence, including complex mixtures and when profiles are subject to dropout.
mixOmics is an R toolkit for the multivariate analysis of biological data, with a specific focus on ‘omics data integration and variable selection.
The best genomic predictor we can find, for individual genotype data and both binary and quantitative traits. Generalises the classical BLUP approach and largely retains its computational efficiency.
BIMBAM for genetic association analysis of multiple related phenotypes.
Wavelet-based genetic association analysis of functional phenotypes arising from high-throughput sequencing assays.
The Missense Tolerance Ratio measures the purifying selection acting on missense variants. Interactive plots and downloads available for 18,000+ genes.
Genomic Databases Resource Hub
Melbourne Integrative Genomic’s I.T. blog (COGENT) is a genomic resource hub used to store tutorials, information about genomic databases and contact information that is regularly used by our group and collaborators. COGENT contains video recordings of our fortnightly computational tutorials and in-depth background on major genomic datasets available online, managed by Bobbie Shaban (Genomic Data Specialist, MIG).